Protective effects of decay-accelerating factor on blast-induced neurotrauma in rats
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چکیده
منابع مشابه
Protective effects of decay-accelerating factor on blast-induced neurotrauma in rats
BACKGROUND Blast-induced neurotrauma (BINT) is the signature life threatening injury of current military casualties. Neuroinflammation is a key pathological occurrence of secondary injury contributing to brain damage after blast injury. We have recently demonstrated that blast-triggered complement activation and cytokine release are associated with BINT. Here, we evaluated if administration of ...
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A majority of investigations on primary blast injuries have focused on gas-containing organs, while the likelihood of blast-induced neurotrauma remains underrated. In Norway minke whales (Balaenoptera acutorostrata) are hunted using small fishing boats rigged with harpoon guns, which fire harpoons tipped with a grenade containing a charge of 30-g penthrite. The grenade detonates 60-70 cm inside...
متن کاملBlast-Induced Neurotrauma Models and Their Requirements
Although advances are being made in identifying some of the essential mechanisms that may lead to chronic neurological deficits after blast-exposure(s), clinical needs continue to exceed current knowledge. In their current article, Brenner and colleagues address the importance of basic science in guiding new diagnostic and treatment strategies. Together with Wilkinson et al., they emphasize one...
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ژورنال
عنوان ژورنال: Acta Neuropathologica Communications
سال: 2013
ISSN: 2051-5960
DOI: 10.1186/2051-5960-1-52